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An insufficient supply of essential amino acids increases the body's need for non-essential amino acids, which it must obtain from the diet

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Common research applications include in-vitro fibroblast and keratinocyte studies, animal wound-healing models, hair-follicle and dermal-papilla research, post-procedure skin-recovery models, antioxidant-pathway investigations, and gene-expression profiling

J Biol Chem 290(14):87788788